Behind the scenes of destroying cancer cells: Analysis of Teledyne e2v technical solution

The three most common treatments for tumors are surgery, chemotherapy, and radiation. The operation is traumatic and the operation is difficult in some areas. Chemotherapy uses chemical drugs to eliminate tumors. After the drugs enter the human body, they are distributed throughout the body. The range of adaptation is large, but the side effects are also large. Radiotherapy uses high-energy killing of cancer cells with the focus of multiple beams of radiation, which is an important means of treating cancer. The MG5193 magnetron and the MG7095 magnetron are the core components of the radiotherapy accelerator. On average, a quarter of a second of cancer patients are treated for this type of product.

The Teledyne e2v is the founder of the magnetron, whose magnetron products provide peak power from 1 MW to 5 MW to radiotherapy accelerators, which are used to generate X-rays to destroy cancer cells. The product itself has relevant professional certification (such as RoHS, etc.), and has been promoted and used in many well-known medical accelerator manufacturers, such as Varian, Elekta and Anke Rui, and integrated with the system to obtain FDA / CFDA and CE Such as international and domestic certification, its products are applied to more than 90% of medical accelerators.

Teledyne e2v has been developing and manufacturing microwave magnetrons for more than 60 years. Around the core of magnetrons, they developed the corresponding all-solid-state pulse modulator power supply technology and developed the entire RF subsystem. The RF subsystem mainly includes: all-solid-state modulator power supply, magnetron, electromagnet/permanent magnet, square-circle conversion, transmission waveguide, four-terminal looper and AFC unit. The whole technical scheme is shown in the figure below.

Behind the scenes of destroying cancer cells: Analysis of Teledyne e2v technical solution

This RF subsystem integrates the world's most advanced all-solid-state power technology, combined with the Teledyne e2v native magnetron, to provide a stable output for the full power range for different applications. The left image below shows the pulse voltage (blue) and pulse current (green) waveforms of our all-solid-state modulator output. The picture on the right is our core product 3.1MW peak power MG7095 magnetron.

Behind the scenes of destroying cancer cells: Analysis of Teledyne e2v technical solution

Teledyne e2v's unique RF subsystem solution uses all-solid-state modulator switching power supply technology and high-power S-band magnetron technology. In general, its technical advantages are:

Compact design integration and testing: small size, modular operation, and remote diagnostic capabilities.

No impedance matching problem: traditional linear modulators or solid-state modulators with pulse transformers have to consider the impedance matching relationship between the power supply and the magnetron due to the pulse transformer as the isolation and boosting device. Once this matching relationship When it is broken, it will cause the magnetron to work in a mismatched state, causing the magnetron to jump or even catch fire. The solution using an all-solid-state modulator can fundamentally solve this problem, and the impedance matching problem does not need to be considered in the entire power output range, and the waveform flat top remains unchanged.

The pulse waveform is more stable and the output dose rate is higher: the solid-state modulator greatly improves the flatness of the pulse compared with the conventional modulator, and reduces the electronic frequency drift effect between the magnetron pulses, so that each from low to high The X-ray dose rate of the power point output is more stable; because the output power is further improved, the customer can obtain a larger dose rate on the original basis and shorten the treatment time of the cancer patient.

Shorten customer development cycle: After using this RF subsystem, customers can directly debug with their core devices, greatly shortening the entire cycle of R&D, enabling customers to quickly introduce new products and seize market opportunities.

Avoiding the inconvenience caused by customers' own selection: The core of the solution is the integration of the unique advantages of Teledyne e2v integration, which is produced under strict quality certification system, avoiding customers' problems in many selection suppliers. Anxiety, equivalent to Teledyne e2v forwards the potential debugging contradiction of the customer's own selection, so that after the customer takes over, he can rest assured that the important debugging process will be carried out later.

Teledyne e2v currently provides customers with comprehensive technical support in all aspects of pre-sales and after-sales. In the pre-sales phase, we closely follow the customer's positioning, provide customers with feasible technical solutions and recommendations for excellent products; in the after-sales phase, according to the needs of customers, engineers can quickly go to the customer site for technical support. Since 2015, we have launched the most advanced microwave test platform and various professional test instruments, such as spectrum analyzers, power meters, network analyzers, etc., at our production base in Beijing, which can provide customers from device level to system level. Complete test service. ”

The RF subsystem's solution uses Teledyne e2v's exclusive technology to develop and integrate, which is the industry's first. In the field of medical accelerator microwave power source products, Teledyne e2v is a world-class industry benchmark. Teledyne e2v not only provides customers with standard microwave system solutions or products, but also provides customized services to customers.

In addition, the high-power S-band magnetron MG8076 is the latest product of Teledyne e2v (below left). The main feature of this magnetron is that it can output up to 7.5MW of pulse power and 7.5KW of average power; the center frequency is 2998Mhz. Working more than one thousandth; magnetron length 0.59m, weight about 13Kg; compact size, especially suitable for compact space, low cost but high dose rate or penetration effect applications. The following is the basic model of the MG8076 magnetron and associated electromagnets. Customers can also match the relevant permanent magnets according to their needs (below right).

Behind the scenes of destroying cancer cells: Analysis of Teledyne e2v technical solution

Recently, Teledyne e2v held a grand opening ceremony at the operation center of Chaoyang District, Beijing. This expansion and investment will serve our business partners more effectively, greatly increasing the supply and technical support of Teledyne e2v in the radiation therapy platform. . "As customer demand for our products and technology increases, the expanded operations center will provide our customers in the Asia Pacific region with better and more comprehensive localization technology services to further enhance productivity and continue to be radiotherapy, security and other High-power RF applications provide technical and application support services. Beijing's production base not only provides customers with a full range of RF products, but also provides fast technical support for new product development at the customer site. Currently the Beijing team can provide customers with Production and assembly of semi-finished products of microwave subsystems, providing professional technical services such as local inventory and localized procurement.

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