Mass spectrometry (MS) has been researched and developed for more than one hundred years. Since scientists discovered that charged particles can be separated by electromagnetic fields based on the charge-to-mass ratio (Q/M). Although there are many types of mass spectrometry systems, their performance depends to a large extent on several basic elements. In modern mass spectrometers, there are usually ion sources (excited ions used to analyze substances), mass analyzers, particle detectors, and related electronic components.
REMPI application
In mass spectrometry, the ion source plays a key role in determining the type of sample. Resonance-enhanced multiphoton ionization (REMPI) technology offers great potential for the pharmaceutical industry. REMPI is based on laser gas phase spectroscopy combined with ab initio calculation of molecules such as neurotransmitters to generate precise structural information.
The result is a rigorous platform to understand the behavior, fundamental and rational drug design of molecules. Resonant two-photon ionization technology allows electron (and IR) mass spectrometry to measure molecular cooling to a few degrees Kelvin. This can make the molecule conform to a beautiful, simplified spectrum.
The technique relies on a time-of-flight mass spectrometer, in which specific ions are selected based on their time of arrival. The picture shows the REMPI mass spectrometry system, developed by Latrobe University in Melbourne, Australia.
solution
This instrument uses Spectrum's 250 MS/s, 14-bit PCIe data acquisition card (model M3i.4121-exp) for data acquisition, display and analysis. The figure below shows the setting window of the instrument and the screenshot of the spectrum acquisition. Digitizer control and data analysis are developed by users based on LabVIEW.
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